Cell membranes with very small passages, such as the placental and blood-brain barriers, affect which pharmacokinetic processes?
a. Absorption
b. Distribution
c. Metabolism
d. Excretion
ANS: B
Once a medication is absorbed, it must travel throughout the body via circulating body fluids to their sites of action. This process is called distribution. The bloodstream and lymphatic system usually carry the drug throughout the body. The organs that have the greatest blood supply receive the medication faster, and areas of skin and fat receive the medication more slowly.
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