A client is receiving thyroid hormone replacement therapy which increases the number of beta1- and beta2-adrenergic receptors. The nurse knows that this increase in receptors will make the receptors more responsive to which neurotransmitters?

Standard Text: Select all that apply.
1. Norepinephrine
2. Epinephrine
3. Dopamine
4. Serotonin
5. Melatonin


Correct Answer: 1,2,3
Rationale 1: Thyroid hormone increases the number of beta1- and beta2-adrenergic receptors and enhances their affinity to catecholamines such as norepinephrine.
Rationale 2: Thyroid hormone increases the number of beta1- and beta2-adrenergic receptors and enhances their affinity to catecholamines such as epinephrine.
Rationale 3: Thyroid hormone increases the number of beta1- and beta2-adrenergic receptors and enhances their affinity to catecholamines such as dopamine.
Rationale 4: Thyroid hormone does not make receptors more responsive to serotonin.
Rationale 5: Thyroid hormone does not make receptors more responsive to melatonin.
Global Rationale: Thyroid hormone increases the number of beta1- and beta2-adrenergic receptors and enhances their affinity to catecholamines such as norepinephrine, epinephrine, and dopamine. This therapy does not make receptors more responsive to serotonin or melatonin.

Nursing

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