Which of the following are manifestations that are characteristic of rheumatoid arthritis and help distinguish it from osteoarthritis? (Select all that apply.)
a. Early morning stiffness
b. Heberden's nodes
c. Activity increases pain
d. Low-grade fever
e. Involvement of other major organs
f. Autoimmune disease
ANS: A, D, E, F
A, D, E, F. Rheumatoid arthritis is a systemic autoimmune disease with morning stiffness, low-grade fever, and organ involvement. B. Heberden's nodes are seen in osteoarthritis. C. Pain increases with activity in osteoarthritis.
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