A patient is diagnosed with acute pancreatitis. The nurse realizes that the basic mechanism behind this disease process is which of the following?
1. autodigestion of pancreatic and surrounding tissues by pancreatic enzymes
2. inability of the pancreas to produce insulin
3. inhibition of kallikrein
4. systemic hypertension caused by increased blood flow to the pancreas
1
Rationale: Acute pancreatitis develops when pancreatic enzymes become prematurely activated resulting in autodigestion of the pancreas and surrounding tissues. Acute pancreatitis is not caused by the pancreas's inability to produce insulin. The activation of kallikrein, and not the inhibition of kallikrein, causes systemic hypotension.
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