The substance produced by the stomach that is necessary for absorption of cobalamin is
a. intrinsic factor.
b. pernicious factor.
c. hydrochloric acid.
d. pyridoxal phosphate.
A
The substance produced by the stomach that is necessary for absorption of cobalamin is intrinsic factor. Pernicious factor does not exist; pernicious anemia is caused by cobalamin deficiency. Hydrochloric acid is produced by the stomach, but is used to activate the enzyme pepsin (which helps digest proteins). Pyridoxal phosphate is the active form of pyridoxine or vitamin B6; it is not produced by the stomach or related to absorption of cobalamin.
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