The post-surgical patient is experiencing delayed wound healing. The dietitian believes the delay is related to nutritional intake. A deficiency in which of the following substances could directly affect healing?
a. Vitamin D
b. Ascorbic acid
c. Melanin
d. Cholesterol
ANS: B
Most of the factors that interfere with the production of collagen in healing tissues are nutrition-al. Scurvy, for example, is caused by lack of ascorbic acid—one of the cofactors required for collagen formation by fibroblasts. The results of scurvy are poorly formed connective tissue and greatly impaired healing. Healing is not associated with vitamin D, melanin, or cholesterol.
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