Based on the gene and protein sequences that follow, what type of mutation has occurred and what is the effect on the polypeptide?
Normal gene: ATGGCCGGCCCGAAAGAGACC
Mutated gene: ATGGCCGGCACCGAAAGAGACC
Normal protein: Met-Ala-Gly-Pro-Lys-Glu-Thr
Mutated protein: Met-Ala-Gly-Thr-Glu-Arg-Asp
A. base addition - silent
B. substitution - missense
C. base addition - missense
D. substitution - nonsense
E. base addition-frameshift
E. base addition-frameshift
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Fill in the blank(s) with the appropriate word(s).
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a. in the arrangement of their covalent bonds b. in their molecular formulas c. by being mirror images that cannot be superimposed on each other d. by having double covalent bonds instead of single bonds e. by having different atomic isotopes in their molecules
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Fill in the blank(s) with the appropriate word(s).