Which of the following is false regarding the GI tract and drug absorption?
A) pH partitioning influences absorption.
B) The presence of food in the stomach or intestine influences absorption.
C) Protein solubility influences absorption.
D) Blood flow influences absorption.
C) Protein solubility influences absorption.
Regarding the GI tract and drug absorption, protein solubility does NOT influence absorption. However, absorption is influenced by pH partitioning, the presence of food in the stomach or intestine, and blood flow. The term pH partitioning refers to a drug's molecules being more likely to be ionized in the plasma, because of differences between plasma pH and the pH at the site of administration.
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