Stimulation of protein kinase A (PKA) signaling pathway produces positive inotropic effects to the heart. Which of the following molecular targets is/are phosphorylated by PKA?
A. Ryanodine receptors (RyR2)
B. SERCA2
C. L-type Ca channels
D. Phospholamban
E. Na-K-ATPase
Ans:
A. Ryanodine receptors (RyR2)
C. L-type Ca channels
D. Phospholamban
You might also like to view...
The gastrointestinal system is a common target organ for MODS related to
a. anorexia. b. limited or absent food ingestion. c. disruption of the mucosal barrier from hypoperfusion. d. a decrease in hydrochloric acid secretion.
What dietary suggestion does the nurse give the older patient to manage age-related changes in taste?
a. Add more salt to foods. b. Use a salt substitute. c. Add sugar when possible. d. Use a variety of herbs.
Which question would be most appropriate to ask when attempting to determine a 6-year-old child's ability to establish trusting relationships after being diagnosed with an anxiety disorder?
a. "Do you like making new friends?" b. "Is it important to be liked by people?" c. "What would you do if your favorite toy got broken? d. "How do you feel when you can't have something you want?"
The stiff, sickled RBCs tend to cause vascular occlusions with subsequent local infarction. As a rule, the spleen suffers so many vaso-occlusive/infarction episodes that it is greatly reduced in size and is rendered nonfunctional by the time the individual is 6 years of age. What are the implications of having a nonfunctioning spleen?