The cytomegalovirus (CMV) produces cytopathic effects (CPE) in diploid fibroblast cells in an average of 7 days. The results are available within 16 hours using which type of assay?
a. Conventional cell culture
b. Shell vial
c. Paired sera
d. Western blot
B
CMV can be detected in clinical specimens using conventional cell culture, shell vial assay, an-tigenemia immunoassay, or molecular methods. CMV produces CPE in diploid fibroblast cells in 3 to 28 days, averaging 7 days. CMV shell vial assay sensitivity is equivalent to conventional cell culture, and the results are available within 16 hours.
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time, forming an easily recognized visual display.
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