A client diagnosed with Barrett esophagus might require the most efficient pharmacologic therapy of GERD. This would include the use of which class of drug?
1. Proton pump inhibitor
2. Antacid
3. Magnesium citrate
4. H2-receptor antagonist
Correct Answer: 1
Rationale 1: The proton pump inhibitors reduce acid secretion to a greater extent than do the H2-receptor antagonists and have a longer duration of action.
Rationale 2: Antacids are not as effective in treating GERD as are proton pump inhibitors.
Rationale 3: Magnesium citrate generally is used as a cathartic and is not indicated for use in the treatment of GERD.
Rationale 4: H2-receptor antagonists are not as effective in treating GERD as are proton pump inhibitors.
Global Rationale: The proton pump inhibitors reduce acid secretion to a greater extent than do the H2-receptor antagonists and have a longer duration of action. Antacids are not as effective in treating GERD as are proton pump inhibitors. Magnesium citrate generally is used as a cathartic and is not indicated for use in the treatment of GERD.
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