You are a scientist for the Federal Drug Administration (FDA). An agricultural company wants to market a new pesticide they have developed for use on produce in the United States. This pesticide is hydrophilic, has a small molecular weight (it is slightly smaller than glucose), and it does not bind to any proteins. Which of the following is an appropriate hypothesis for how this drug will be found in the body?
A. The pesticide will mostly be cleared in the feces as it will bind to cholesterol, which is added to the GI tract.
B. The pesticide will mostly be cleared in the urine as it will be filtered but not reabsorbed.
C. The pesticide will be cleared through the skin as it will diffuse through the skin layers and evaporate from the surface.
D. The pesticide will remain in the blood for a long period as it is not filtered or secreted by the urinary tract.
Answer: A
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