The nursing instructor teaches the nursing students about neural mechanisms of pain. What does the nursing instructor teach about substance P?
1. Substance P modifies sensory information in the spinal cord.
2. Substance P is also known as an endogenous opioid.
3. Substance P stimulates pain receptors in the spinal cord.
4. Substance P controls which pain signals reach the brain.
4
Rationale 1: Endogenous opioids, not substance P, modify sensory information at the level of the spinal cord.
Rationale 2: Substance P is not an endogenous opioid.
Rationale 3: Substance P does not stimulate pain receptors in the spinal cord.
Rationale 4: Spinal substance P is critical because it controls whether pain signals will continue to the brain.
Global Rationale: Spinal substance P is critical because it controls whether pain signals will continue to the brain. Endogenous opioids, not substance P, modify sensory information at the level of the spinal cord. Substance P does not stimulate pain receptors in the spinal cord. Substance P is not an endogenous opioid.
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