A child, age 10 years, has a neuroblastoma and is in the hospital for additional chemotherapy treatments. What laboratory values are most likely this child's
a. White blood cell count, 17,000/mm3; hemoglobin, 15 g/dl
b. White blood cell count, 3,000/mm3; hemoglobin, 11.5 g/dl
c. Platelets, 450,000/mm3; hemoglobin, 12 g/dl
d. White blood cell count, 10,000/mm3; platelets, 175,000/mm3
ANS: B
Chemotherapy is the mainstay of therapy for extensive local or disseminated neuroblastoma. The drugs of choice are vincristine, doxorubicin, cyclophosphamide, cisplatin, etoposide, ifosfamide, and carboplatin. These cause immunosuppression, so the laboratory values will indicate a low white blood cell count and hemoglobin.
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