Which is a birth defect or disorder that occurs as a new case in a family and is not inherited?
a. Sporadic
b. Polygenic
c. Monosomy
d. Association
ANS: A
Sporadic describes a birth defect previously unidentified in a family. It is not inherited. Polygenic inheritance involves the inheritance of many genes at separate loci whose combined effects produce a given phenotype. Monosomy is an abnormal number of chromosomes whereby the chromosome is represented by a single copy in a somatic cell. A nonrandom cluster of malformations without a specific cause is an association.
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