Most cervical cancer originates at the
a. isthmus. c. internal os.
b. squamocolumnar junction. d. lateral fornix.
B
The endocervical canal is lined with mucus-secreting columnar epithelium. The ectocervix, which protrudes into the vagina, is covered with the same squamous epithelial cells that line the vagina. The point at which the two types of cells merge is the squamocolumnar junction. Its exact location varies with age, but it is clinically important because it is the point at which most cervical cancer originates. The isthmus is a constricted area between the body of the uterus and the cervix. The internal os is within the body of the cervix. The lateral fornix is the point where the vagina joins the uterus.
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