A 22-year-old female client has acute uncomplicated cystitis. The nurse knows that which antibacterial would not be an appropriate choice to treat this infection?
1. Trimethoprim-sulfamethoxazole (TMP-SMZ)
2. Metronidazole (Flagyl)
3. Norfloxacin (Noroxin)
4. Fosfomycin (Monurol)
Correct Answer: 2
Rationale 1: Trimethoprim-sulfamethoxazole is a fixed-dose combination sulfonamide, and is the traditional choice for AUC in most communities.
Rationale 2: Metronidazole is a miscellaneous antibacterial that is used to treat protozoal infections, and is often used in the treatment of pelvic infections.
Rationale 3: Norfloxacin is a fluoroquinolone. Fluoroquinolones have become the drug of choice in many communities.
Rationale 4: Fosfomycin blocks cell wall synthesis. Its only indication for use is UTI.
Global Rationale: Metronidazole is a miscellaneous antibacterial that is used to treat protozoal infections, and is often used in the treatment of pelvic infections. Trimethoprim-sulfamethoxazole is a fixed-dose combination sulfonamide, and is the traditional choice for AUC in most communities. Norfloxacin is a fluoroquinolone. Fluoroquinolones have become the drug of choice in many communities. Fosfomycin blocks cell wall synthesis. Its only indication for use is UTI.
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