The nurse knows which of the following statements listed below is accurate regarding the functions and nature of cytokines relative to a variety of pathologies?
A)
"A particular cytokine can have varied effects on different systems, a fact that limits their therapeutic use."
B)
"Cytokine production is constant over time, but effects are noted when serum levels cross a particular threshold."
C)
"Most cytokines are produced by granular leukocytes, and different cells are capable of producing the same cytokine."
D)
"Cytokine actions are self-limiting, in that activation of one precludes activation of other cytokines with similar actions."
Ans:
A
Feedback:
Because cytokines can mediate diverse effects due to their pleiotropic properties, they can have significant side effects. Cytokine production is brief, not constant, and production does not normally take place in granulocytes. Activation of a cytokine does not necessarily limit other similar cytokines, and additive effects are not uncommon.
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