The nurse is educating a client regarding the effects of kidney damage and medications. Which statements by the nurse are appropriate regarding this topic? (Select all that apply.)
Note: Credit will be given only if all correct choices and no incorrect choices are selected.
1. Kidney damage can significantly shorten drug action.
2. Kidney damage does not cause adverse reactions.
3. Kidney damage is a common cause of adverse reactions.
4. Kidney damage can significantly prolong drug action.
5. Kidney damage decreases the metabolism of drugs.
Correct Answer: 3, 4
Rationale 1: Kidney damage can significantly prolong drug action, not shorten drug action.
Rationale 2: Kidney damage can significantly prolong drug action, and is a common cause of adverse reactions.
Rationale 3: Kidney damage can significantly prolong drug action, and is a common cause of adverse reactions.
Rationale 4: Kidney damage can significantly prolong drug action, and is a common cause of adverse reactions.
Rationale 5: Kidney damage does not affect drug metabolism. Liver damage affects drug metabolism.
Global Rationale: Kidney damage can significantly prolong drug action, and is a common cause of adverse reactions. Kidney damage does not affect drug metabolism. Liver damage affects drug metabolism.
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