Under what conditions would antidiuretic hormone (ADH) be present to promote facultative water reabsorption? Specify where in the renal tubule this hormone exerts its effects
What will be an ideal response?
This condition can occur when the body is somewhat dehydrated (higher blood osmotic pressure) and ADH is secreted. ADH creates more aquaporins in the late distal tubule and collecting ducts. Facultative water reabsorption then occurs when the interstitial fluid surrounding the nephron is more concentrated than the filtrate. Water can be reabsorbed from collecting ducts when this concentration gradient is established and when ADH is present. Water is drawn into the interstitial space by osmosis until the interstitial fluid and filtrate are iso-osmotic.
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