Postexposure prophylaxis (PEP) for occupational HIV exposure should be started within what time period after exposure to be most successful?
1. 2 weeks
2. 24–36 hours
3. 36–48 hours
4. 1 week
Correct Answer: 2
Rationale 1: PEP should be started much sooner than 2 weeks after exposure.
Rationale 2: PEP should be started 24–36 hours after exposure to be most successful.
Rationale 3: PEP should be started sooner than 36–48 hours after exposure.
Rationale 4: PEP should be started sooner than 1 week after exposure.
Global Rationale: For prevention to be most successful, PEP should be started within 24 to 36 hours after exposure to a source person who is known to be HIV positive.
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