A patient is having skin testing done to assess for allergies. What would the nurse identify as evidence of exposure to an antigen?
1. itching at the site
2. area approximately 1 mm in diameter of induration and erythema
3. induration and erythema not evident until after 5 days
4. area larger than 10 mm of induration and erythema
Correct Answer: 4
Skin testing can assess cell-mediated immunity. A known antigen is injected intradermally. The site is then observed for induration and erythema, which typically peak at 24 to 48 hours. An induration of at least 10 mm in diameter is a positive reaction that indicates previous exposure and sensitization to the antigen. Itching is not a sign of exposure to an antigen.
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