Which of the following research findings is most consistent with the claim that antidepressants are being overprescribed for treating depression?
A. Between 30% and 60% of patients treated with SSRIs report problems with sexual activity, likely caused by their reduction in the activity of the gaseous neurotransmitter nitric oxide (NO).
B. Depression appears to reduce the number of neurons found in the hippocampus, but antidepressants may both halt this loss and promote the birth of new neurons.
C. When patients fail to respond to antidepressants, other biological treatments might be used to treat MDD, such as ECT, deep brain stimulation, or rtMS.
D. Antidepressant clinical trials as a whole have small (0.30) effect sizes, even when severely depressed individuals are included in the sample.
Answer: D
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