One method for determining if a targeted drug will be effective is to perform a FISH assay on a biopsy of the diseased tissue. How does FISH demonstrate potential efficacy of the drug?
What will be an ideal response?
A FISH assay determines the copy number of the gene for which the fluorescent probe was designed to target. If the target gene is present in a higher than normal copy number, the drug target is likely to be expressed at high levels as well. This suggests that the drug target is present and will respond to the targeted therapeutic.
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Genes that normally prevent cell division are
A) tumor suppressors. B) transcription factors. C) proto-oncogenes. D) oncogenes.
If an organism inherits one dominant and one recessive allele, the phenotype of this organism will look like which of the following?
a. the dominant allele b. the recessive allele c. both the dominant and recessive allele d. neither the dominant or recessive allele
In gel electrophoresis, what causes the DNA fragments to migrate?
A. Gravity D. Magnetic attraction B. Vibrations E. Centrifugal force C. Electrical charge
A species of caterpillar develops toxic spikes that deter the birds that prey on it. Over time, the genetics of the bird population shifts so that an allele for a digestive enzyme that neutralizes the toxin becomes more common
This is an example of A) mutualism. B) an invasive species. C) parasitism. D) coevolution. E) mimicry.