A recent study suggests the surprising idea that intestinal goblet cells present food antigens to dendritic cells to induce tolerance to food molecules. Thus, goblet cell dysfunction may be a cause of food allergies. If this is true, it illustrates the importance of coordination between which two organ systems?
A. immune system and circulatory system
B. circulatory system and endocrine system
C. digestive system and endocrine system
D. digestive system and immune system
Clarify Question
What is the key concept addressed by the question?
What type of thinking is required?
Gather Content
What do you already know about goblet cells and dendritic cells? What other information is related to the question?
Choose Answer
Given what you now know, what information is most likely to produce the correct answer?
Reflect on Process
Did your problem-solving process lead you to the correct answer? If not, where did the process break down or lead you astray? How can you revise your approach to produce a more desirable result?
D. digestive system and immune system
Clarify Question
What is the key concept addressed by the question?
· The concept addressed here is the relationship between two systems of the body.
What type of thinking is required?
· Analyze level:
o This is an analyze question because you have to break dendritic cells and goblet cells into their component pieces to understand how they function.
Gather Content
What do you already know about goblet cells and dendritic cells? What other information is related to the question?
· Dendritic cells are antigen-presenting cells of the immune system. They are also called accessory cells.
· Dendritic cells present antigens to T cells, so an immune response can be formulated against the antigen.
· Goblet cells are found within the mucous membranes of the digestive tract, among other places.
· Goblet cells are known to produce mucus.
Choose Answer
Given what you now know, what information is most likely to produce the correct answer?
· Neither the endocrine system nor the circulatory system gave rise to the dendritic or goblet cells.
· Since dendritic cells are immune cells, the immune system is at work here. The goblet cells in this example are representatives of the digestive system.
Reflect on Process
Did your problem-solving process lead you to the correct answer? If not, where did the process break down or lead you astray? How can you revise your approach to produce a more desirable result?
· Analyze level:
o Answering this question correctly depended not only on distinguishing between dendritic and goblet cells, but on your ability to break down, or analyze, the systems that gave rise to these cells. If you got an incorrect answer, did you remember that components of dendritic cells include immune system functions, or that goblet cells can be components of the digestive tract? Did you have trouble breaking down these cells to determine the correct answer?
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