A client is prescribed isoproterenol for ventricular dysrhythmia. Which concurrent medication order would cause the nurse to question the order for isoproterenol?
1. Analgesic
2. MAO inhibitor
3. Cardiac glycoside
4. Anti-inflammatory drug
Correct Answer: 2
Rationale 1: Analgesics do not affect any action of isoproterenol.
Rationale 2: Isoproterenol is metabolized by COMT and MAO in the liver; hence MAO inhibitors should be discontinued two weeks prior to isoproterenol therapy to prevent hypertensive crisis.
Rationale 3: Cardiac glycosides do not affect any action of isoproterenol.
Rationale 4: Anti-inflammatory drugs do not affect any action of isoproterenol.
Global Rationale: Isoproterenol is metabolized by COMT and MAO in the liver; hence MAO inhibitors should be discontinued two weeks prior to isoproterenol therapy to prevent hypertensive crisis. Analgesics, cardiac glycosides, and anti-inflammatory drugs do not affect any action of isoproterenol.
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