Which of the following goals of mechanical ventilatory support of parenchymal lung injury have resulted in significant improvement in outcomes? I. accepting lower Pao2 values II. allowing lower pH values III. employing aggressive PEEP-Vt combinations IV using lower tidal volumes

A. I, II only
B. II, IV only
C. I, II, IV only
D. I, III, IV only


ANS: C
A. Incorrect response: See explanation C.
B. Incorrect response: See explanation C.
C. Correct response: The goals of mechanical ventilatory support of parenchymal lung injury have shifted over the last decade to providing smaller tidal volumes, and accepting consequently lower arterial values for Po2 and the development of respiratory acidosis. These goals have resulted in significant improvements in outcomes.
D. Incorrect response: See explanation C

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