Describe the difference between a vesicular and a nonvesicular synapse?

What will be an ideal response?


Vesicular synapses, also termed chemical synapses, are by far the most abundant; there are several different types.
Most interactions between neurons and all communications between neurons and peripheral effectors involve
vesicular synapses. At a vesicular synapse between neurons, a neurotransmitter released at the presynaptic
membrane of a terminal bouton binds to receptor proteins on the postsynaptic membrane and triggers a transient
change in the transmembrane potential of the receptive cell. Only the presynaptic membrane releases a
neurotransmitter. As a result, communication occurs in one direction only: from the presynaptic neuron to the
postsynaptic neuron.
Nonvesicular synapses, also termed electrical synapses, are found between neurons in both the CNS and PNS, but
they are relatively rare. At a nonvesicular synapse, the presynaptic and postsynaptic membranes are tightly bound
together, and gap junctions permit the passage of ions between the cells. Because the two cells are linked in this
way, they function as if they shared a common membrane, and the nerve impulse crosses from one neuron to the
next without delay. In contrast to vesicular synapses, nonvesicular synapses can convey nerve impulses in either
direction.

Anatomy & Physiology

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