A client is prescribed octreotide (Sandostatin) but has no evidence of acromegaly. The nurse realizes that this medication is indicated for which other health problems?
Standard Text: Select all that apply.
1. Severe diarrhea
2. Portal hypertension
3. Bleeding esophageal varices
4. Pancreatic fistulas
5. Diabetes mellitus
Correct Answer: 1,2,3,4
Rationale 1: Octreotide (Sandostatin) stimulates the absorption of fluid and electrolytes from the gastrointestinal tract and is approved to treat severe diarrhea.
Rationale 2: Octreotide (Sandostatin) decreases hepatic and gastrointestinal blood flow and reduces hepatic-portal venous pressure. This makes the medication useful to treat portal hypertension.
Rationale 3: Octreotide (Sandostatin) decreases hepatic and gastrointestinal blood flow and reduces hepatic-portal venous pressure. This makes the medication useful to treat bleeding esophageal varices.
Rationale 4: Octreotide (Sandostatin) is used off label to reduce the output from pancreatic fistulas.
Rationale 5: Octreotide (Sandostatin) is not used to treat diabetes mellitus.
Global Rationale: Octreotide (Sandostatin) stimulates the absorption of fluid and electrolytes from the gastrointestinal tract and is approved to treat severe diarrhea. It also decreases hepatic and gastrointestinal blood flow and reduces hepatic-portal venous pressure, making it useful to treat portal hypertension and esophageal varices. Octreotide (Sandostatin) is used off label to reduce the output from pancreatic fistulas. It is not used to treat diabetes mellitus.
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