While discussing embryogenesis to a group of students moving through the maternity ward, the nurse quizzes them to see if they know what is happening during sonic hedgehog signaling. Which of the following answers would be considered accurate?

Question

Select all that apply.
A)
Development of the eyes
B)
Separation of the brain into two cerebral hemispheres
C)
A carrier system for delivering the appropriate amino acids to the ribosomes
D)
Development of the correct number of fingers and toes
E)
Bone formation leading to macrocephaly

Answer 1

Ans:
B, D

Feedback:

Sonic hedgehog signaling is involved in many key developmental events at multiple times during embryogenesis. It participates in such diverse developmental steps as establishment of the left-to-right axis responsible for the rostral-caudal orientation of the nervous system, the separation of the brain into two cerebral hemispheres, right and left eye orientation, and the separation and development of the correct number of fingers and toes. The PAX family of transcription factors is responsible for the development of the eye. Transfer RNA acts as a carrier system for delivering the appropriate amino acids to the ribosomes. Bone formation leading to macrocephaly is caused by fibroblast growth factors.