Jimmie is a heavy drinker. He admits to drinking 12-pack of beer a night. He has been diagnosed with cirrhosis of the liver during his latest physical besides already having hypertension

a. What is cirrhosis of the liver and what can Jimmie expect?
b. List the complications of cirrhosis of the liver.
c. What is the prognosis for this disease?
d. What is the treatment?


Students' answers should include the following:
a. Cirrhosis is a chronic and degenerative disorder of the liver with cellular damage.
b. Irreversible and partial or complete obstruction of blood vessels due to fibrous scar tissue replacing liver cells
Digestion, metabolism, blood coagulation, electrolyte and fluid imbalances, inability to detox chemicals, and inability to metabolize hormones
Alcoholic, postnecrotic, and biliary cirrhosis; alcoholic is the most common type.
Necrotic liver cells are replaced by scar tissue.
Develops over 30 years or longer
c. Prognosis is based on albumin and bilirubin levels, along with presence of ascites, neurologic status, and nutritional status.
Compensated—vague s/s and less severe
Uncompensated—more pronounced and liver failure indicated
Fatigue, anorexia, dyspepsia, nausea, vomiting, constipation, weight loss, and diarrhea
White to clay-colored stools due to no bile in GI tract; dark or tea-colored urine
Liver biopsy reveals hepatic fibrosis.
Esophageal varices life threatening
Portal hypertension
Ascites
d. Banding or balloon tamponade for varices
Stents for portal hypertension

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