Tadalafil [Cialis] was prescribed 4 weeks ago for a patient with erectile dysfunction. The patient also takes prazosin [Minipress] for hypertension. Which statement by the patient best demon-strates understanding of the use of tadalafil [Cialis]?
a. "I can take this up to 2 times a day, just before intercourse."
b. "I have a little renal trouble, so I should take a higher dose."
c. "I should take this medication with food."
d. "I should take this medication no more than once a day."
D
Tadalafil should be taken no more than once a day and without regard to meals. Tadalafil has a half-life of 17.5 hours and should not be taken twice a day. Men with moderate renal or hepatic insufficiency should take a reduced dosage. This patient may be confusing the actions of tadalafil and prazosin.
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