A client with the sex-linked (X-linked) recessive form of muscular dystrophy asks what this means for his children. What is the nurse's best response?
A. "Only your sons are at risk for this form of muscular dystrophy."
B. "None of your children will get the disease, but your daughters may pass it on to their sons."
C. "Only children you conceived after you developed muscular dystrophy are at risk for developing this disease."
D. "Your children are not at risk for getting the muscular dystrophy unless your wife also has the disease."
B
In sex-linked (X-linked) recessive disorders, the disease is passed on the X chromosome. It is expressed in males when the X chromosome carries the defective gene, because males have only one X chromosome. No offspring of the affected males will express the disease. The daughters who inherit the defective X chromosome have a 50% risk of passing the disease on to their sons.
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