A client received an injection of norepinephrine as part of medical treatment. This neurotransmitter will be destroyed by which body organs?
Standard Text: Select all that apply.
1. Kidney
2. Liver
3. Stomach
4. Bladder
5. Pancreas
Correct Answer: 1,2
Rationale 1: Norepinephrine that enters circulation as a medication is destroyed by the enzyme catechol-O-methyltransferase in kidney cells.
Rationale 2: Norepinephrine that enters circulation as a medication is destroyed by the enzyme catechol-O-methyltransferase in liver cells.
Rationale 3: Norepinephrine that enters circulation as a medication is not destroyed by the stomach.
Rationale 4: Norepinephrine that enters circulation as a medication is not destroyed by the bladder.
Rationale 5: Norepinephrine that enters circulation as a medication is not destroyed by the pancreas.
Global Rationale: Norepinephrine that enters circulation as a medication is destroyed by the enzyme catechol-O-methyltransferase in kidney and liver cells. Norepinephrine that enters circulation as a medication is not destroyed by the stomach, bladder, or pancreas.
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