After several cycles of lab testing on test animals, a medication can enter clinical trials for evaluation in humans. In phase one clinical trial testing:

A) the trial is expanded to include a large sample size, usually in the thousands of individuals, and establish the overall safety and effectiveness of the drug.
B) the medication is compared to other medications on the market.
C) consists of the drug being tested on a small number (usually 300 or less) of people with the illness or condition the drug is designed to treat.
D) researchers attempt to determine the safe dose and how the medication is both absorbed and eliminated from the body.


Answer: D

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