After administering cyclophosphamide to a client the nurse should:
a. continue to monitor the client's urine pH.
b. administer leucovorin to decrease serum uric acid.
c. administer mesna to rescue the bladder.
d. add sodium bicarbonate to the IV fluids.
ANS: C
Feedback
A Incorrect: The nurse should continue to monitor urine specific gravity.
B Incorrect: This is appropriate for methotrexate administration.
C Correct: Cyclophosphamide can cause hemorrhagic cystitis, so mesna is administered immediately after cyclophosphamide administration and at prescribed intervals for 24 hours.
D Incorrect: The is associated with methotrexate.
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