In contrast to most dsDNA animal viruses, the poxviruses replicate solely in the cytoplasm of the host cell. What does this suggest about the virus?

What will be an ideal response?


All cellular DNA replication occurs in the nucleus. DNA polymerases are synthesized in the cytoplasm and are transported into the nucleus where they are active. Replication of viral DNA in the cytoplasm would require DNA polymerase activity take place in the cytoplasm. One possibility is that the viral genome includes a gene for a DNA polymerase and that a DNA polymerase enzyme is packaged in the virion. Otherwise, the virus has some mechanism for diverting cellular DNA polymerase to the cytoplasm. The first possibility is the simpler explanation.
Bloom's Taxonomy: Analysis
Section: Viral Replication
Learning Outcome: 13.11

Biology & Microbiology

You might also like to view...

As you and a friend are entering a chemistry laboratory at your university, you see a sign that states: DANGER—RADIOACTIVE ISOTOPES IN USE. Your friend is an accounting major and has not had any science courses yet. She asks you what a radioactive isotope is and you respond correctly with:

A. Radioactive isotopes are atoms that are unstable and as a result emit energy in a process called radioactive decay. B. Radioactive isotopes are atoms that are stable and as a result emit energy in a process called radioactive decay. C. Radioactive isotopes are atoms that are stable and as a result only emit energy if they are exposed to higher temperatures. D. Radioactive isotopes are atoms that are unstable but unless actively disturbed by some chemical process will remain intact and pose no problems.

Biology & Microbiology

Which of the following organisms would most likely produce asexually?

A. a worker honeybee B. a lizard in an equatorial desert C. a mammal in a temperate forest D. a bird in an urban environment

Biology & Microbiology

According to the graph, which is likely the factor limiting reproductive output of a female fruit fly?

a) availability of male mates b) time to mate with multiple males c) production of eggs d) eggs are much smaller and delicate than sperm e) males typically choose only one female

Biology & Microbiology

An approach in which scientists make observations about the natural world, develop tentative

explanations about what they observe, and then test those explanations by collecting more information is referred to as ____.

a. science b. education c. the scientific method d. the method e. the biological method

Biology & Microbiology