Gayle, an ICU nurse, has Epstein-Barr and is afraid of having other disorders as complications to this virus. She thinks she might have some of the symptoms of Hodgkin's disease
Discuss Hodgkin's disease and the relationship the Epstein-Barr virus has to it.
a. What are the Reed-Sternberg cells?
b. What organs are affected by this disease?
c. Who is more likely to be affected by this disorder?
d. What are the signs and symptoms?
e. What are the classifications?
f. How it is medically managed?
Students' answers should include the following:
a. Mutations in some lymphocytes, creating malignant cells known as Reed-Sternberg cells
Cytokines are chemicals released from malignant cells.
b. Enlargement of lymphoid tissue, spleen, liver, bone marrow, and lungs
c. Females are affected more than males.
d. Symptoms include enlargement of lymph nodes, usually cervical first; low-grade fever; pruritus; night sweats; thrombocytopenia with anemia; poor resistance to infections; and respiratory issues.
e. Four stages in this disorder; classifications of A and B for general symptoms or no symptoms
f. Radiation, transfusions, and autologous bone marrow or stem cells
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