Rapid detection of SNPs, which are allelic variants, can be accomplished with DNA microarrays

If a microarray is set up for a set of genes, including all variants, outline a general procedure for quickly assaying the genotype of multiple individuals for that set of genes.


DNA taken from the individuals would be cut (restricted) and labeled with fluorescent markers. Once introduced to an array, the probes hybridize where there is sequence complementarity. The fluorescent marker then reveals which allelic variants of the genes of interest are expressed by each individual.

Biology & Microbiology

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Biology & Microbiology