Based on the data obtained from various studies conducted to determine the effect of lung protective strategies to minimize the development of VILI in patients with ALI and ARDS, which of the following conclusions is appropriate?

A. These patients must be ventilated with tidal volumes ranging between 10-12 ml/kg, and Pplateau of around 30 cm H2O.
B. ALI and ARDS patients must be ventilated with tidal volumes around 6 ml/kg, and high level of PEEP.
C Such patients must be ventilated with around 6 ml/kg and a Pplateau near 30 cm H2O.
D. These patients must be ventilated with tidal volumes ranging between 10-12 ml/kg and low levels of PEEP.


?ANS: C
A. Incorrect response: See explanation C.
B. Incorrect response: See explanation C.
C. Correct response: Low tidal volumes are the standard of care for patients with ALI or ARDS. Tidal volumes must be at or near 6 ml/kg predicted body weight. The Pplateau should be maintained at or near 30 cm H2O. The tidal volume should be lowered to a minimum of 4 ml/kg to try to achieve a plateau pressure of 30 cm H2O or less.
D. Incorrect response: See explanation C.

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