What is the Frank-Starling effect, and why is it important during periods of increased end-diastolic volume? What would happen if the Frank-Starling effect didn't exist?

What will be an ideal response?


Answer: The Frank-Starling effect describes the effect whereby greater filling of the ventricles results in a greater ventricular contraction. It allows the ventricles to effectively "autoregulate" stroke volume, so that it can pump effectively. It allows the heart to automatically compensate for increases in the amount of blood returning to the heart. If the Frank-Starling effect didn't exist, and the stroke volume of the heart was always constant, then in a situation in which venous return is increased, there would be "leftover" blood in the heart after each contraction. This extra blood would build up over time, increasing in volume, until the heart was so distended that contraction would be ineffective.

Anatomy & Physiology

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