Tumor necrosis factor-a and IL-1 are major cytokines that mediate inflammation
If the patient is developing a systemic response to an infection, the nurse will likely assess which of the following clinical manifestations? Select all that apply.
A)
Elevated temperature
B)
Hypertension
C)
Tachycardia
D)
Decrease in urine output
E)
Anorexia
Ans:
A, C, E
Feedback:
IL-1 and TNF-a are mediators of the acute-phase responses associated with infection or injury. Features of these systemic responses include fever (elevated temperature), hypotension, tachycardia (increased heart rate), anorexia, increase in neutrophil count, and increased levels of corticosteroid hormones.
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