An adolescent client diagnosed with panic disorder is prescribed paroxetine (Paxil), a selective serotonin reuptake inhibitor (SSRI). The client tells the nurse she often takes diet pills because she is trying to lose weight
Which response by the nurse is the most appropriate?
1. "You can continue with the paroxetine (Paxil) and the diet pills."
2. "It is important to stop both the paroxetine (Paxil) and the diet pills."
3. "Discontinue using the diet pills while taking the paroxetine (Paxil)."
4. "You should discuss the safety of these two medications pills with a pharmacist."
Correct Answer: 3
Rationale: Serotonin syndrome, the serious and life-threatening side effect of SSRIs, can develop when the drug is taken with diet pills, St. John's wort, other antidepressants, alcohol, or LSD. In this case, the diet pills should be discontinued in order to avoid serotonin syndrome. The Paxil should not be discontinued, and waiting to discuss the use of diet pills with a pharmacist would not be an appropriate option.
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