An intensive care unit (ICU) nurse is preparing to administer an intravenous dose of imipenem–cilastatin to a patient who is being treated for sepsis. What aspect of this patient's history would contraindicate the use of this drug?
A) The patient has a history of type 1 diabetes mellitus.
B) The patient is showing signs and symptoms of fluid volume excess.
C) The patient's most recent creatinine level was 140 ?mol/L (high).
D) The patient has a documented allergy to penicillin.
D
Feedback:
It is important to avoid administering imipenem–cilastatin and the other carbapenems to people with life-threatening allergic reactions to penicillin. Diabetes, slightly increased creatinine levels, and fluid overload do not necessarily contraindicate the use of imipenem–cilastatin.
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