(A) What is a cross-match test? (B) Why is it carried out? (C) How is it carried out?

What will be an ideal response?


A. A cross-match test assesses the compatibility between a potential donor and a recipient for blood transfusion.
B. A cross-match test is carried out to ensure that hypersensitivity reactions, such as type II hypersensitivity, do not occur as a result of antibodies in the recipient's blood reacting against blood group antigens on the donor erythrocytes, thus triggering destruction of the transfused red cells.
C. To carry out a cross-match test, blood serum from the recipient (the blood fraction containing antibodies) is mixed with erythrocytes from the donor.

Health & Biomechanics

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