A patient has been diagnosed with a coagulopathy and has been given Coumadin as a mode of treatment. What screening test(s) should be performed to monitor this treatment, and what effect will this therapy have on the coagulation pathway?
a. APTT; initial decrease in the vitamin K-dependent factors of the intrinsic pathway
b. PT-INR; initial decrease in the vitamin K-dependent factors of the extrinsic pathway
c. PT-INR and APTT; initial decrease in the vitamin K-dependent factors of all pathways
d. PT-INR; initial decrease in all vitamin K-dependent serine proteases
Correct Answer: D
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