When explaining the final stages of the inflammatory response to pathogens, the nurse will educate the patient about

A)
how the body can kill the pathogen by generating toxic oxygen and nitrogen products producing such things as nitric oxide and hydrogen peroxide.
B)
margination, which is a process whereby white cells (leukocytes) stick to the endothelium and accumulate along the blood vessel.
C)
the increase in vascular permeability, which lets fluids leak into the extravascular tissues.
D)
the promotion of tissue regeneration whereby monocytes and macrophages produce potent prostaglandins and leukotrienes.


Ans:
A

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The latter stages of phagocytosis results in intracellular killing of pathogens accomplished by several mechanisms, including toxic oxygen and nitrogen products, lysozymes, proteases, and defensins. The metabolic burst pathways generate toxic oxygen and nitrogen products (i.e., nitric oxide, hydrogen peroxide, and hypochlorous acid). Margination is one of the early stages of the inflammatory response. Vascular changes occur with inflammation but are prior to the final stage. Macrophages arrive within hours at the inflammation site.

Nursing

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