Which of the following parameters is important in determining the optimal level of positive end expiratory pressure (PEEP) in a patient with ARDS?

a. PaO2
b. SaO2
c. DO2
d. CaO2


ANS: C
As with increasing PEEP, improvements in arterial oxygenation attendant to reducing PCWP must be weighed against reduced cardiac output, as reflected by the measured DO2 or other measures of systemic tissue oxygenation.

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