An older adult is receiving the highly protein-bound drug phenytoin (Dilantin). Compare the fol-lowing effects and choose the one that describes changes this drug will undergo owing to the effects of aging on blood components
a. Greater biotransformation, making smaller amounts of the drug necessary
b. Greater biotransformation, making greater amounts of the drug necessary
c. Less biotransformation, making smaller amounts of the drug necessary
d. Less biotransformation, making greater amounts of the drug necessary
ANS: B
Drug distribution and equilibration rates are affected by changes of aging that alter protein bind-ing, volume of distribution, amount of body fat present, and regional perfusion patterns. Re-duced plasma protein levels can result in higher concentrations of unbound drug, especially when the drug competes with other protein-bound drugs. As a result, more unbound drug circulates, increasing the action of highly protein-bound drugs, but this effect is not always predictable.
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Your client complains of discomfort in the lower abdomen. She describes it as a sharp pain below the umbilicus on one or both sides of the uterus. You hypothesize that the client is experiencing which of the following?
a. True labor pains c. Round ligament dis-comfort b. Periodic labor pains d. Braxton-Hicks con-tractions
The nurse notes that the tongue of the client who has undergone a Billroth II operation has taken on a shiny, beefy appearance. What conclusion can the nurse draw from this informa-tion?
A. The client requires further instruction regarding postoperative oral hygiene. B. The client is exhibiting symptoms of vitamin B12 deficiency. C. The client has developed protein-calorie malnutrition. D. The client is exhibiting symptoms of alkaline reflux.
A standard hypodermic needle is calibrated
A. in units. B. in ounces. C. in millimeters. D. in cubic centimeters.
Which tasks would be appropriate for the nurse to delegate to unlicensed assistive personnel (UAP)?
1. Taking vital signs 2. Measuring and recording intake and output 3. Postmortem care 4. Providing telephone advice 5. Weighing the client