Neomycin (Mycifradin sulfate) is ordered for the patient who is to undergo bowel surgery. Which of the following purposes would accurately explain to the patient the action of this drug and why it is being used preoperatively?
a. To restore electrolyte balance
b. To promote osmotic diuresis
c. To decrease the gastrointestinal (GI) tract bacterial count
d. To inhibit ammonia elimination
ANS: C
Neomycin is an ammonia-detoxifying drug because it kills ammonia-producing bacteria in the GI tract. For this reason, it can also be used to decrease the bacterial count in the GI tract before bowel surgery.
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